The Rupestrian Sanctuary of the Holy Spirit is an underground church dated between the 12th and 13th centuries. It stands on the side of an ancient riverbed, Lama Don Angelo, to the south-west of the town of Monopoli.

As a result of researches, studies and excavations in the santeliano countryside, the dynamics of medieval settlements have been reconstructed and traced. To date, the investigations, mostly concentrated on the high ground of Pianisi, have brought to light several testimonies and remains of the inhabited area with large sections of the walls of the upper terracing of the fortified village, the great tower that dominates the inhabited area and the church of Santa Maria ad Nives with its bell tower.