In Samnite and Roman times, in Molise there was a dense network of fortifications, the perimeter walls could reach the length of several kilometers, located on the heights of the domain of the valleys and the ancient streets. The fortifications were made in polygonal work, with dry stone walls set with blocks of local stone not worked. The presence of towers incorporated in the walls, does not seem to be a characteristic of the Samnite fortifications, with the exception of Le Tre Torrette di Campochiaro, here in fact, along the walls there are the ruins of three towers.

The Augustan Amphitheater of Lucera is one of the most ancient and largest in Southern Italy and accounts for the most important Roman ruins in all of Puglia.